For this procedure, the part of the brain containing the point at which the seizures start is removed. It is important to clarify the nature of insults that most likely have ca… Remove from your own thinking disease/remedy relations, like for viral/ seasonal flus, Gels, Ars, Acon, or for joint pains, Rhus tox, Bry etc. Temporal lobe seizures are often associated with auras of nausea, emotions (such … It also appears that the mesial temporal sclerosis can be worsened by additional seizures. As of Jan 2015 he has got his job back and the last MRI done to see the vascularity of his brain was normal. To schedule an appointment with one of our brain or spine experts, please call 1-844-NSPC-DOC. Mesial temporal sclerosis usually results in partial (focal) epilepsy. Déjà vu 1.4. I don’t feel that fearful now, the piloerection also comes in a mild manner, the chilliness is there, but less, the slurring speech is also there but less.”. I feel sleepy and miserable after these drugs. Age at onset Late childhood or adolescence. Our team of expert doctors focuses on sophisticated diagnostic techniques, individualized treatment plans, and quality care to help you get your life back, sooner. He now complained of a headache whenever he woke up from sleep, on the left side of the head, dull aching and it would go off after about 1-2 hrs. What is Mesial Temporal Sclerosis? Neuroimaging allows our expert brain surgeons to carefully target the damaged tissue and allow as much healthy brain tissue to remain as possible. These seizures last from a few seconds to 2 minutes. In this patient it was a left sided temporal sclerosis. I told him not to worry and to stop those antiepileptics right away. Fatigue Talk to our Chatbot to narrow down your search. Gelsemium and Lachesis are wonderful drugs. Hi mam, my son 13 yrs old boy. Most patients present with complex partial temporal lobe epilepsy. Generally, hippocampal sclerosis may be seen in some cases of epilepsy, particularly temporal lobe epilepsy. He came to me on the 22nd of July 2014 and I asked him to explain in detail what he exactly felt in those 2 -5 minutes. There is no blood flow obstruction, but the plain MRI still shows that atrophic scar in the deepest part of left temporal lobe. Before the seizure: 1.1. Our offices are now open for in-person appointments. Difficulty speaking 3.4. But the cause is not always known. Gelsemium LM2 was given twice a day, and on the 4th day he said- “I was feeling a lot better, the whole episode has almost vanished; there are no such symptoms of chilliness, wave etc, but now since the last dose I feel more lethargic and dull and tired , even though I felt better earlier.” Lebensjahr auf. Statistically, febrile seizure is the most strongly related to mesial temporal sclerosis symptomatology 12,14,16-18. Hello mam, Introduction.Mesial temporal lobe epilepsy (MTLE) associated with hippocampal sclerosis is highly refractory to clinical treatment. This damage is thought to be a significant cause of temporal lobe epilepsy. After the seizure: 3.1. Causes and Symptoms of Mesial Temporal Sclerosis, Surgical Treatments for Mesial Temporal Sclerosis, Connect with our 7 convenient locations across Long Island, NY, strange sensations such as seeing auras or, Request a Our expert physicians, surgeons and doctors are ready to serve you at our 7 convenient locations across Long Island, NY. OBJECTIVE. Jerking motion of the fingers 2.2. In der Mehrzahl der Fälle liegt neuropathologisch eine mesiale temporale Sklerose vor, verändert sind der Hippocampus, die angrenzenden Hirnwindungen und der Mandelkern. Hippocampal sclerosis also commonly referred to as mesial temporal sclerosis, is the most common brain pathological lesion underyling intractable temporal lobe epilepsy 1).. Hippocampal sclerosis is the commonest cause of drug-resistant epilepsy in adults, and is associated with alterations to structures and networks beyond the hippocampus 2). Surgical treatments for intractable epilepsy include a temporal lobectomy or vagal nerve stimulation. Certainly the medicine had worked but the patient was still suffering, so now I decided to use the LM scale of potencies. I am in my forties now and have treated many complex cases. Who knew that reversal of neuronal damage manifestations could be initiated by Yellow Jasmine? Neurological and mental state Usually normal prior to seizure onset. Case Report: A 38 yr old male who was overweight had been seeing me for the past 10 years off and on for his health issues, mainly ureteric calculi, and pain in the renal region, at times left and other times right. MRI scan commonly displays increased T2 signal and hippocampal atrophy Mesial temporal sclerosis might occur with other temporal lobe abnormalities (dual pathology). If you neglect that approach, you can lose the match! He immediately stopped his bike and stood up. Although the hippocampal sclerosis is commonly found among elderly people (≈10% of individuals over the age of 85 years), association between this disease and ageing remains unknown. TLE and mesial temporal sclerosis (MTS) were characterized by significant increases in OSTOX (MDA, AOPP, LOOH) and lowered ANTIOX (-SH groups, TRAP). During this period, I have a feeling of anxiety and fear also. Although mesial temporal sclerosis (MTS) is the most frequent refractory epilepsy in adults with temporal lobe epilepsy,¹ the same does not happen with children where the cause is less frequent. Sometimes a lack of oxygen, an infection, trauma or continuing seizures contribute to the development of mesial temporal sclerosis. So, hippocampal sclerosis, mesial temporal sclerosis, could be easily scarred inside the temporal lobe. On 16.04.17, she reported acute pain in lower left abdominal region and than fainted with biting of lips etc. But I am not even able to use the fan, because if I do so, this episode comes earlier than 20 minutes. Temporal lobectomy is a surgical procedure to remove the brain tissue in the temporal lobe that is causing the seizures. MRI Report On 17th July 2014 after which antiepileptics were given. The relationship, if any, of mesial temporal sclerosis with febrile seizures is controversial, made all the more difficult due to the relative insensitivity of imaging and the difficulty in establishing whether a particular seizure was truly febrile. 1 Homeopathy Journal – It’s Free! Seizures. Checked Clarks Dictionary of Practical Materia Medica and could not find much. During the seizure: 2.1. Clinical manifestations Pre-existing complex febrile convulsions are common. I love to experience nature with all its flora and fauna. 3 Antiepileptic agents offer complete seizure control in some of these patients. My family and I are in great distress, since I have been told by the neurologist that I am not supposed to drive, since I may black out and fall from a scooter or my car may meet an accident under the influence of these anti epileptics drugs. The region begins to atrophy; neurons die and scar tissue forms. SYMPTOMS Mesial temporal sclerosis usually results in partial (focal) epilepsy. Lip smacking 2.3. During this time the feeling of coldness is so great that I have to cover the left side of my body with a blanket, even though it is the heat of summer, and the right side I leave uncovered. Unaware of surroundings 3. This seizure disorder can cause a variety of symptoms such as strange sensations, changes in behavior or emotions, muscle spasms, or convulsions.The seizures usually are localized in the brain, but they may spread to become generalized seizures, which involve the entire brain and may cause a sudden loss of awareness or consciousness. Memory loss 3.3. Einteilung. There is slight dilatation of the right temporal horn as compared to the left. Clinical studies suggest that prolonged seizures or complicated febrile seizures may result in MTS. For Saltik et al. my daughter(7 year old) was diagnosed that she as F/S/O Left mesial temporal sclerosis. On the other hand, it is an often unrecognized cause of cognitive decline, typically presenting with severe memory loss. A simple medicine can initiate cure even of a complicated disorder. This is a community dedicated to those of us who suffer with Mesial Temporal Sclerosis. Verbreitung. He has been in the habit of chewing gutka, (tobacco product) and paan masala (contains Betel leaf) for the past 6-8 yrs and also takes alcohol daily, for the past 3-4 years. This is what he said: –“While in this episode I started to shiver with a feeling of coldness and almost shuddering of only the left side of the body. Now a dose of Gelsemium 200 was given, and the patient was asked to wait in my clinic. My wife is 33 yr. Old. For about 6 days the patient took those drugs only to realise that there was no reduction in those uncomfortable symptoms, and now some new symptoms had also come up. In fact, 70 percent of temporal lobe epilepsy patients have some degree of mesial temporal sclerosis. For the past year he has been healthy otherwise. All the symptoms have gone, and health is restored. Sometimes a lack of oxygen, an infection, trauma or continuing seizures contribute to the development of mesial temporal sclerosis. Signs and symptoms of focal aware seizures include: Déjà vu (a feeling of familiarity), a memory, or jamais vu (a feeling of unfamiliarity) Sudden sense of fear or anxiety, anger, sadness, joy Apart from the chronic nature of epilepsy, hippocampal sclerosis was sho… The hair on my left arm stands up (piloerection), and then a wave like sensation of fluttering originating from left side of chest and moving both up and down on left lower limb and left upper limb and towards the face, also left sided and lacrimation from left eye, and during this time I get that slurred speech if I try to speak. Vagal Nerve Stimulation is a minimally invasive mesial temporal sclerosis treatment that employs an implanted stimulator to deliver electric impulses to an electrode on the vagal nerve in the neck via a lead wire implanted under the skin. After paying the bill of 15000/- Rs he went back home only to realise now that he also had a slur in his speech for those 2- 5 minutes when the abnormal sensations in his chest were experienced. This seizure disorder can cause a variety of symptoms such as strange sensations, changes in behaviour or emotions, muscle spasms, or convulsions and memory loss. I took MRI and test mentioned as follows “features are suggestive of right mesial temporal sclerosis”. I don’t want to hear the sound of T.V. Also since I am taking these anti-epileptic drugs, that neurologist has given me, now even if a dog barks, I get startled and fearful. Euphoria 1.3. Check the full list of possible causes and conditions now! Wave-like sensation which travels upwards and downwards to the left upper and lower limbs from the chest. Depression 3.2. This seizure disorder can cause a variety of symptoms such as strange sensations, changes in behaviour or emotions, muscle spasms, or convulsions and memory loss. The area where the arrow points is the scarring of the neuronal tissue. He was rushed the same night to a nearby hospital for fear of a heart attack and was admitted for observation for the night to look for any cardiac cause. He went on having the sensation for about 2-5 minutes and then it subsided , only to reoccur every 20- 30 minutes. Sudden or strange odor or taste 1.6. Connect today to learn how our award winning, world class experts can help. The revolutionary NeuroPace RNS® System uses a pacemaker, similar to ones used in deep brain stimulation to treat Parkinson’s disease, to employ electrial stimulation to normalize brain activity. Symptoms of mesial temporal sclerosis are generally associated with focal (partial) epilepsy, such as. Mesial temporal lobe sclerosis contributes to a significantly compromised quality of life for many patients. Moreover, a recent study revealed that 7 (41%) of 17 epilepsy patients with SLE had mesial temporal lobe epilepsy (MTLE) (Toyota et al., 2013). The percentage of seizure-free patients was 24.2% (22 of 91 patients) at the second visit which was held up to 5 years after the first visit. Hi Madam, Dr. Aparna Singh - I am a homoeopathic doctor practising this wonderful healing method for the past 23 years. 19 talking about this. Contact us today for an appointment or consultation. The next day he was discharged from the hospital and told that the ECG was normal and his symptoms were not related to cardiac cause. It … -SURGERY-The assessment of the extent of mesial temporal sclerosis is important because it can be a good indicator of the outcome for patients undergoing temporal lobectomy to control seizures. MTS is the most common cause of structural epilepsy and focal seizures in the temporal lobe. It was Lachesis. With no further repetition, I sent him away with placebo for 2 days. He gets no exercise and has a fatty liver. Visit our premier treatments centers in the NY and Long Island areas to talk with one of our experienced neurospecialists. Homoeopathy is the science of symptoms. Febrile seizures. consultation, Our Mesial Temporal Sclerosis Symptom Checker: Possible causes include Medial Sclerosis. Brain damage from traumatic injury, infection, a brain tumor, a lack of oxygen to the brain, or uncontrolled seizures is thought to cause the scar tissue to form, particularly in the hippocampus, a region of the temporal lobe. Now his symptoms were demanding another perfect match/simillimum. An optimized high-resolution MRI, like the ones we use at our epilepsy centers in the NY area, can show mesial temporal sclerosis that other general MRIs often miss. Subscribe to world’s No. Mesial temporal sclerosis usually results in partial (focal) epilepsy. It just fit every bit of the puzzle. Temporal lobe epilepsy (TLE) is a chronic disorder of the nervous system characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes. Etiology Hippocampal sclerosis. The objective of this study is a revision of literature about mesial temporal sclerosis in children. Hippocampal sclerosis cases were more likely than Alzheimer’s disease to have had a history of stroke or hypertension, (evidence of small vessel disease) but less likely to have had diabetes mellitus. I passed out from Nehru Homoeopathic Medical College in New Delhi in the May 1992 and earned a gold medallion for excellence in the academic study of Homoeopathy. Had been excreting calculi from the urinary tract until one year ago. Die Temporallappenepilepsie gilt als die häufigste Epilepsieform, sie tritt erstmals zwischen dem 5. und 10. Simple focal seizures are the initial non-febrile seizures followed by Seizure frequency is significantly associated with … MRI Scan suggest MTS, EEG is normal. Mesial temporal sclerosis is the most common pathological abnormality in temporal lobe epilepsy. Hippocampal sclerosis. A CPS is often preceded by an aura. Aft 2 days he came back and said, “Now the gap in between the episodes has increased, and also the intensity of symptoms is much less. Dr. Aparna Singh MRI voxel-based morphometry (VBM) of T1-weighted images has revealed a widespread pattern of gray matter (GM) and white matter (WM) atrophy in MTLE. These impulses modulate the brain’s circuitry. Follow up of children with febrile seizures does not demonstrate signifi… The seizures usually are localized in the brain, but they may spread to become generalized seizures, which involve the entire brain and may cause a sudden loss of awareness or consciousness. MATERIAL AND METHODS . Unprovoked fear 2. Gelsemium is the perfect match (coldness, shivering, wave like sensation which travels up and down, slurring of speech, dull and lethargic). As well as Murpheys Materia Medica. A variety of epileptogenic agents administered to adult animals have resulted in MTS and spontaneous recurrent seizures. Up to a third of patients with established refractory temporal lobe epilepsy have a history of seizures in childhood at the time of fever 3. The condition called mesial temporal sclerosis is closely related to temporal lobe epilepsy, a type of partial (focal) epilepsy in which the seizure initiation point can be identified within the temporal lobe of the brain. Apart from the chronic nature of epilepsy, hippocampal sclerosis was shown to have an important role in internal cardiac autonomic dysfunction. I started to analyse the case to pick out the characteristic totality which would form the basis of my prescription. After about 40 minutes he got that conglomeration of signs and symptoms again, so the 1st improvement noticed was the time lag, instead of 20 minutes, it came aft 40 minutes. 3 For example, the risk of mesial temporal sclerosis developing from childhood complex febrile seizures is 3%. An amygdalohippocampectomy is the surgical removal of the amygdala and the hippocampus after other treatments have failed to provide relief. The most common pathology in surgically resected specimens is that of mesial temporal sclerosis (gliosis and scarring in the mesial temporal lobe). The neurophysician prescribed anti epileptic drugs. 19, the febrile seizure is associated with MTS mainly when seizures start early or are present as complex febrile seizures or even as status febrile. We are now In-Network with The Empire Plan (NYSHIP). The etiology of mesial temporal sclerosis is unclear. Clinical presentation. Mesial temporal sclerosis is the loss of neurons and scarring of the deepest portion of the temporal lobe and is associated with certain brain injuries. The discrimination of pure TLE from controls yielded a significant area under the ROC curve for MDA (0.999), AOPP (0.851), -SH groups (0.899), and the OSTOX/ANTIOX ratio (0.996). Also, the presence of bilateral mesial temporal sclerosis and additional extrahippocampal temporal abnormalities were not related to prognosis. Mesial temporal lobe epilepsy is the most common form of human epilepsy, and its pathophysiological substrate is usually hippocampal sclerosis, the most common epileptogenic lesion encountered in patients with epilepsy. Sex Males = females. Copyright © 2020. The seizures usually are localized in the brain, but they may spread to become generalized seizures, which involve the entire brain and may cause a sudden loss of awareness or consciousness. If you can rationally think and catch the symptoms, you catch the remedy. On 15th July 2014, it was a hot summer day, and at noon he was riding his bike when he experienced some abnormal sensation of fluttering in the left side of his chest. Miasm consideration is not necessary, when the totality is characteristic and speaks for the remedy. [casemed.case.edu] It is an important diagnosis to recognize as these patients can often be made seizure free with surgical resection of … He was again put on placebo, and he went on improving steadily till November 2014. Rising sensation in the abdomen 1.5. Hpathy Medical Publishers. More common are complex partial seizures (CPSs) in which the patients lose consciousness and have sensory, mental, visceral, and somatomotor symptoms. Was achieved a bibliographic revision using Medline data base … I present cases in the IIHP meetings here in Dehradun, the capital of the Himalayan state of India, Uttarakhand. The neurophysician ordered an MRI which revealed that there was scar/atrophic tissue/dead neuronal tissue, in the deepest part of the left temporal lobe/hippocampus. The peculiarity was that he would get this left sided headache even after he woke up from an afternoon nap. Mesial Temporal Sclerosis (MTS) is a term used to describe scarring in deep part of the temporal lobe of the brain. For over 50 years & 350,000 patients NSPC has been a trusted global medical leader. Our highly-qualified, board-certified neurosurgeons and epilepsy specialists provide expert mesial temporal sclerosis, hippocampal sclerosis, and associated temporal lobe epilepsy. A focal seizure in the temporal lobe may spread to other areas in the brain when it may become a focal to bilateral seizure. Studies suggest an increased incidence among family members and an association with precipitating insults during the first four to five years of life. Atrophy/scar in brain remains but the symptoms vanish. Under such a medical term as “hippocampal sclerosis”, specialists understand one of the forms of epileptic pathology caused by damage to the limbic system of the brain. Don’t let mobility issues and neck or back pain stop you — NSPC offers exceptional rehabilitation and pain management for your spine disorder. consultation, Request a Although temporal lobe seizures are always partial, they can become secondarily generalized and result into tonic–clonic seizures (Mathern et al., 1996). It is seen in up to 65% of autopsy studies, although significantly less on imaging. Please suggest us medicines which can cure it. Medical scans such as PET (positron emission tomography) scans or SPECT (single-photon emission computed tomography) scans and electroencephalograms (EEGs) can help determine where the sclerosis is and where the seizures originate. Of note, sclerosis of mesial temporal lobe structures (mesial temporal sclerosis, MTS), ... 2000), sixty patients with TLE were subdivided according to mesial versus neocortical temporal sclerosis, and depressive symptoms were assessed using the self‐reported Beck Depression Inventory (BDI). Lachesis LM2 was given twice a day for 4 days, after which he reported complete relief of the headache. Histopathological hallmarks of hippocampal sclerosis include segmental loss of pyramidal neurons, granule cell dispersionand reactive gliosis. The changes associated with mesial temporal sclerosis are usually identifiable on a magnetic resonance imaging (MRI) scan. Seizures in temporal lobe epilepsy start or involve in one or both temporal lobes in the brain. Mesial temporal sclerosis (MTS), also commonly referred to as hippocampal sclerosis, is the most common association with intractable temporal lobe epilepsy (TLE) 2,3,5. Homeopathy for Multiple Sclerosis Treatment, Homeopathy for Cerebral Palsy Symptoms Treatment, Reversal of Multiple Sclerosis in a Woman of 53. Now also lethargic and dull after 6 days of anti-epileptic therapy. This means that pyramidal neuronal cells are lost, granule cells are spread widely or driven off, and glial cells are changed in response to damage to the central nervous system (CNS). I used to take alcohol and tobacco products daily but since the day this has started to occur, I have stopped taking them. Pl suggest. It is a nice case well presented. Die mesiale temporale Sklerose, auch als Hippokampussklerose oder Ammonshornsklerose bezeichnet, ist der häufigste neuropathologische Befund bei der therapierefraktären Temporallappenepilepsie.. Sie wurde erstmals 1825/26 von den beiden französischen Psychiatern Camille G. Bouchet und Jean Baptiste Cazauvieilh mit bloßem Auge erkannt, später u. a. These imaging findings are compatible with mesial temporal sclerosis on the right. In young individuals, it is commonly recognized as Mesial temporal sclerosis with Temporal Lobe Epilepsy (TLE). However I want to ask you from which source book did you get the information on Gelsemium. Your selection of medicine is very accurate. Columbia Resident Writes (a Chapter of) the Book on Cavernous Malformations Columbia Sends out Press Release on Department’s Aneurysm Research Columbia Spine Surgeons Mentioned in NJ Magazine Columbia Team Presents Picture of the Month in Archives of Pediatric Medicine Columbia to Host ‘Advances in Brain Tumor Management’ Symposium for Neurosurgeons Columbia Voted #1 Medical … Dr. Aparna Singh presents a case of Mesial Temporal Sclerosis in which the symptoms were reversed with homeopathic treatment. Mesial temporal sclerosis treatments generally consist of managing the epilepsy symptom by using either anticonvulsant medication or, if medication is not effective, surgery. High anxiety symptoms are independently associated with epilepsy as well as focal/unknown epilepsy and mesial temporal sclerosis, according to study results published in Epilepsy & Behavior. Prevalence ~20% of patients with epilepsies; 65% of mesial TLE. Mesial temporal sclerosis (MTS), which involves neuronal loss and gliosis within the mesial temporal structures (primarily in Sommer sector and the CA4 region of the hippocampus), 1 is an important cause of temporal lobe epilepsy. I love to share my cases to inspire and motivate young doctors with cures based on the principles laid down in the Organon. It can be a cause of seizures. What is to be learnt here? An aura or far-away look 1.2. Most patients present with complex partial temporal lobe epilepsy. MTS affects the hippocampus which is the brain region that is involved in memory formation and retrieval and the amygdala which is involved in emotional processing. MTLE typically causes seizures that last 30 seconds to two minutes and may include: 1. He subsequently consulted a neurology specialist in the town. Location, Trigeminal Neuralgia and Face Pain Center. Even a homoeopath can bungle a case if totality is not considered (or if miasm is considered in lieu of totality). After about 2 to 5 minutes these sensations/episode passes off on its own, only to return aft 20 minutes. The disease is also known as mesial temporal sclerosis. … In Nov 2014, there was a change of symptom picture. TLE is the most common form of epilepsy with focal seizures. Patients with left hippocampal sclerosis had more severe parasympathetic dysfunction as compared with those with right hippocampal sclerosis. He eats rich food and is a non vegetarian. A far-away, glazed look 2.4. Symptoms of mesial temporal sclerosis are generally associated with focal (partial) epilepsy, such as. There were also observations that hippocampal sclerosis was associated with vascular risk factors. But the cause is not always known.